Among these lesions, stroke accounts for the highest proportion. Lesions in the central nervous system often led to dysregulation of colon function and a lack of coordination in the anal sphincter muscles. All items from the World Health Organization Trial Registration Data set are described in this manuscript. This registration was completed on May 23, 2023. The study has been registered in the Chinese Clinical Registry under the number ChiCTR2300071709. The findings will provide information that can contribute to the formulation of bowel management strategies. This study aims to evaluate the effectiveness and safety of a bowel rehabilitation program for stroke patients with NBD. Furthermore, secondary outcomes measure will be assessed, including Bristol score, Patient Assessment of Constipation-Quality of Life (PAC-QoL), and Fecal Incontinence Quality of Life (FI-QoL). The primary outcome measures will be the Wexner score. The duration of the intervention for both groups will be 6 weeks. The control group will receive standard care, while the intervention group will undergo a program that combines DRS and abdominal massage in addition to standard care. This study follows a prospective randomized controlled parallel-group clinical trial design. Although current guidelines suggest a conservative strategy for addressing bowel dysfunction, which includes techniques such as digital rectal stimulation (DRS) and abdominal massage, the availability of interventions remains limited in healthcare facilities. Neurogenic bowel dysfunction (NBD) is a prevalent complication among stroke patients, significantly affecting their quality of life, duration of hospitalization, medical expenses, and even mortality.
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